Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK74874.1ECF-family protein RNA polymerase sigma factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; match to protein family HMM TIGR02957; Belongs to the sigma-70 factor family. (304 aa)    
Predicted Functional Partners:
pcaC-7
4-carboxymuconolactone decarboxylase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
  
 0.714
ABK73033.1
Alkylhydroperoxidase AhpD core; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
  
 0.694
ABK73911.1
Transcriptional regulatory protein; Identified by match to protein family HMM PF00196.
  
  
 0.585
ABK72938.1
Putative ECF sigma factor RpoE1; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
 
   
 0.531
rshA
Anti-sigma factor, family protein; A redox-regulated anti-sigma factor for cognate extracytoplasmic function (ECF) sigma factor SigH. ECF sigma factors are held in an inactive form by an anti-sigma factor (Probable). Overexpression leads to increased susceptibility to diamide.
  
 
 0.481
ABK74419.1
Conserved hypothetical protein.
  
 
 0.478
rseA
Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigE. ECF sigma factors are held in an inactive form by an anti-sigma factor (By similarity); Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.
  
 
 0.466
ABK70777.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
   
 0.457
ABK70259.1
Cupin domain protein; Identified by match to protein family HMM PF07883.
  
    0.451
ABK72869.1
3-oxoacyl-[acyl-carrier-protein] reductase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF07993.
  
  
 0.436
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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