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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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ABK72550.1Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (264 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.991
add
Adenosine deaminase; Identified by match to protein family HMM PF00962; match to protein family HMM TIGR01430; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
 
 0.985
hpt
Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 0.983
ABK74942.1
Guanine deaminase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
 
 
 0.974
ABK72836.1
Adenosine kinase; Identified by match to protein family HMM PF00294.
  
 
 0.968
ABK71738.1
Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156.
  
 0.955
pncB
Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.942
surE
Acid phosphatase SurE; Identified by match to protein family HMM PF01975; match to protein family HMM TIGR00087.
    
 0.942
sir2
NAD-dependent deacetylase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.
    
 0.941
ABK76102.1
Nicotinamidase/pyrazinamidase; Identified by match to protein family HMM PF00857.
    
 0.940
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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