Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK76143.1RNA polymerase sigma-70 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa)    
Predicted Functional Partners:
ABK73312.1
Conserved hypothetical protein; Identified by match to protein family HMM PF06172.
       0.773
ABK74146.1
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
   
 
 0.661
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.650
rshA
Anti-sigma factor, family protein; A redox-regulated anti-sigma factor for cognate extracytoplasmic function (ECF) sigma factor SigH. ECF sigma factors are held in an inactive form by an anti-sigma factor (Probable). Overexpression leads to increased susceptibility to diamide.
  
 
 0.530
ABK71088.1
6-hydroxy-D-nicotine oxidase; Identified by match to protein family HMM PF01565.
       0.509
ABK72359.1
RNA polymerase sigma-70 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.485
ABK76201.1
RNA polymerase ECF-type sigma factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.481
ABK74419.1
Conserved hypothetical protein.
  
 
 0.478
rseA
Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigE. ECF sigma factors are held in an inactive form by an anti-sigma factor (By similarity); Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.
  
 
 0.466
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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