Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK74586.1Endonuclease VIII and dna n-glycosylase with an ap lyase activity; Identified by match to protein family HMM PF01149; match to protein family HMM PF06827; match to protein family HMM PF06831; Belongs to the FPG family. (252 aa)    
Predicted Functional Partners:
ABK70223.1
DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
 
  
 0.979
ABK75773.1
Putative formamidopyrimidine-DNA glycosylase; Identified by match to protein family HMM PF01149; match to protein family HMM PF06831; Belongs to the FPG family.
  
  
 
0.950
ABK70524.1
HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.
     
 0.824
ABK75527.1
Transcriptional regulator; Identified by match to protein family HMM PF01022.
      
 0.809
ABK71481.1
Conserved hypothetical protein.
      
 0.798
ABK74084.1
DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573.
  
 
 0.782
ABK75396.1
HNH endonuclease; Identified by match to protein family HMM PF01844; match to protein family HMM PF02720.
     
 0.736
ABK74532.1
HNH nuclease, putative.
     
 0.735
ABK73995.1
H-N-H endonuclease F-TflIV.
     
 0.735
recA
Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...]
  
  
 0.710
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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