Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK72542.1Piperideine-6-carboxylic acid dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (527 aa)    
Predicted Functional Partners:
gabT-3
4-aminobutyrate transaminase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00700; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.883
ABK75920.1
Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family.
   
 0.866
ABK70896.1
L-lysine-epsilon aminotransferase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.861
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.857
mmsB
3-hydroxyisobutyrate dehydrogenase; Identified by match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR01692; Belongs to the HIBADH-related family.
  
 
 0.844
ABK73456.1
Amine oxidase [flavin-containing] B; Identified by match to protein family HMM PF01266; match to protein family HMM PF01593.
   
 0.838
ABK72054.1
Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.834
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.832
ABK71405.1
Glycerate kinase; Identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; Belongs to the glycerate kinase type-1 family.
   
 
 0.832
acyP
Acylphosphatase; Identified by match to protein family HMM PF00708.
    
 0.831
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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