Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABK74935.1Conserved hypothetical protein. (174 aa)    
Predicted Functional Partners:
ABK73764.1
Conserved hypothetical protein.
  
     0.661
ABK73695.1
Polysulphide reductase, NrfD; Identified by match to protein family HMM PF03916.
  
    0.604
ABK69542.1
YghA protein; Identified by match to protein family HMM PF03458.
       0.601
ABK74447.1
4Fe-4S ferredoxin, iron-sulfur binding protein; Identified by match to protein family HMM PF00037.
  
    0.562
ABK75922.1
Manganese containing catalase; Identified by match to protein family HMM PF05067.
 
   
 0.539
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) repair enzyme which repairs blunt-end and 5'-overhang double strand breaks (DSB) with about 50% fidelity, and DSB with non-complementary 3' ends. Plays a partial role in NHEJ on 3'-overhang repair of complementary ends. NHEJ repairs DSB with blunt ends and 5' overhangs with a high level of nucleotide insertion/deletion, without a need for microhomology. This protein but not LigD also suppresses homologous recombination. Overexpression dramatically increases the efficiency of NHEJ with no effect on repair fidelity.
 
     0.487
ABK71601.1
Ribonuclease inhibitor.
   
    0.412
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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