Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lpqBLpqB protein; May modulate activity of the MtrAB system in controlling homeostasis of the cell wall and cell division. Belongs to the LpqB lipoprotein family. (585 aa)    
Predicted Functional Partners:
mtrB
Sensor histidine kinase MtrB; Member of the two-component regulatory system MtrA/MtrB. Probably functions as a membrane-associated protein kinase that phosphorylates MtrA in response to environmental signals (By similarity). MtrB may be active only at septa where it promotes MtrA phosphorylation and MtrA regulon expression, probably playing a role in cell division.
 
  
 0.976
mtrA
DNA-binding response regulator MtrA; Member of the two-component regulatory system MtrA/MtrB, responding to environmental signals (Probable). Controls expression of a number of genes including dnaA, ripA, fbpB and probably itself. Probably plays a role in cell division.
     
 0.892
ABK73363.1
Bacterial extracellular solute-binding protein, family protein 5; May directly or indirectly regulate the accessibility of the key branch point intermediate, monoacyl phosphatidylinositol tetramannoside (AcPIM4), to the elongating alpha-1,6 mannosyltransferases which could regulate the lipoarabinomannans (LAMs) biosynthesis; Belongs to the bacterial solute-binding protein 5 family.
  
   
 0.802
ABK76216.1
Conserved hypothetical protein.
 
     0.780
ABK70327.1
Conserved hypothetical protein.
 
     0.773
ABK72891.1
Conserved hypothetical protein.
 
     0.770
ABK70520.1
Probable conserved membrane protein.
      
 0.767
ABK70482.1
LprC protein.
  
     0.764
ABK72090.1
Conserved hypothetical protein.
  
     0.762
ABK75913.1
Putative membrane protein.
  
     0.759
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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