ABK72021.1 protein (Mycolicibacterium smegmatis)

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Score

ABK72021.1

Identified by match to protein family HMM PF00300. (203 aa)

Predicted Functional Partners:

ABK69697.1

0.867

ABK74748.1

0.865

thyA

0.859

ABK69693.1

0.729

ABK75945.1

0.671

nadK

0.556

gpmA

0.549

ABK75639.1

0.532

cobS

0.527

ABK75142.1

0.524

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK69693.1	ABK69697.1	MSMEG_1927	MSMEG_1925	Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656.	Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.	0.783
ABK69693.1	ABK72021.1	MSMEG_1927	MSMEG_1926	Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656.	Identified by match to protein family HMM PF00300.	0.729
ABK69693.1	ABK74748.1	MSMEG_1927	MSMEG_1924	Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656.	N-acetyltransferase Ats1; Identified by match to protein family HMM PF00583.	0.695
ABK69693.1	ABK75945.1	MSMEG_1927	MSMEG_1928	Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656.	Identified by match to protein family HMM PF00481.	0.848
ABK69693.1	thyA	MSMEG_1927	MSMEG_2670	Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.425
ABK69697.1	ABK69693.1	MSMEG_1925	MSMEG_1927	Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.	Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656.	0.783
ABK69697.1	ABK72021.1	MSMEG_1925	MSMEG_1926	Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.	Identified by match to protein family HMM PF00300.	0.867
ABK69697.1	ABK74748.1	MSMEG_1925	MSMEG_1924	Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.	N-acetyltransferase Ats1; Identified by match to protein family HMM PF00583.	0.861
ABK69697.1	ABK75639.1	MSMEG_1925	MSMEG_4193	Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.	Identified by match to protein family HMM PF00300.	0.818
ABK69697.1	ABK75945.1	MSMEG_1925	MSMEG_1928	Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.	Identified by match to protein family HMM PF00481.	0.540
ABK72021.1	ABK69693.1	MSMEG_1926	MSMEG_1927	Identified by match to protein family HMM PF00300.	Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656.	0.729
ABK72021.1	ABK69697.1	MSMEG_1926	MSMEG_1925	Identified by match to protein family HMM PF00300.	Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.	0.867
ABK72021.1	ABK74748.1	MSMEG_1926	MSMEG_1924	Identified by match to protein family HMM PF00300.	N-acetyltransferase Ats1; Identified by match to protein family HMM PF00583.	0.865
ABK72021.1	ABK75142.1	MSMEG_1926	MSMEG_5270	Identified by match to protein family HMM PF00300.	Cystathionine beta-synthase; Identified by match to protein family HMM PF00291; match to protein family HMM PF00571; match to protein family HMM TIGR01137.	0.524
ABK72021.1	ABK75639.1	MSMEG_1926	MSMEG_4193	Identified by match to protein family HMM PF00300.	Identified by match to protein family HMM PF00300.	0.532
ABK72021.1	ABK75945.1	MSMEG_1926	MSMEG_1928	Identified by match to protein family HMM PF00300.	Identified by match to protein family HMM PF00481.	0.671
ABK72021.1	cobS	MSMEG_1926	MSMEG_4277	Identified by match to protein family HMM PF00300.	Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.	0.527
ABK72021.1	gpmA	MSMEG_1926	MSMEG_0935	Identified by match to protein family HMM PF00300.	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.	0.549
ABK72021.1	nadK	MSMEG_1926	MSMEG_3750	Identified by match to protein family HMM PF00300.	Inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NADkinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.556
ABK72021.1	thyA	MSMEG_1926	MSMEG_2670	Identified by match to protein family HMM PF00300.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.859