STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mimAPropane monooxygenase hydroxylase large subunit; Component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane. Also involved in the degradation of acetone via the O2-dependent hydroxylation of acetone. Also able to catalyze the oxidation of phenol, methylethylketone (2-butanone), 1-propanol and 2-propanol. (542 aa)    
Predicted Functional Partners:
mimB
Methane monooxygenase component C; Reductase component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane. Reductase catalyzes the transfer of electrons from NADH or NADPH to monooxygenase (Probable).
 
 
 0.997
mimD
Propane monooxygenase coupling protein; Effector component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane.
 
 
 0.994
mimR
Sigma factor; Acts as a transcriptional activator of the mimABCD operon encoding the propane 2-monooxygenase complex.
 
  
 0.974
ABK72265.1
Alcohol dehydrogenase; Identified by match to protein family HMM PF00107.
 
 
  0.912
ABK72679.1
Toluate 1,2-dioxygenase electron transfer component; Identified by match to protein family HMM PF00106; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF07729; match to protein family HMM PF08021.
  
 
  0.827
ribBA
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.817
ABK70753.1
Conserved hypothetical protein; Identified by match to protein family HMM PF01883.
 
    0.799
ABK75152.1
Amidohydrolase 2; Identified by match to protein family HMM PF04909.
 
     0.781
ABK71349.1
Rieske [2Fe-2S] domain, putative; Identified by match to protein family HMM PF00355.
 
  
  0.780
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
  0.775
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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