Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK75152.1Amidohydrolase 2; Identified by match to protein family HMM PF04909. (347 aa)    
Predicted Functional Partners:
ABK70753.1
Conserved hypothetical protein; Identified by match to protein family HMM PF01883.
 
    0.958
ABK72265.1
Alcohol dehydrogenase; Identified by match to protein family HMM PF00107.
 
  
 0.953
mimD
Propane monooxygenase coupling protein; Effector component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane.
 
     0.930
mimB
Methane monooxygenase component C; Reductase component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane. Reductase catalyzes the transfer of electrons from NADH or NADPH to monooxygenase (Probable).
 
  
  0.782
mimA
Propane monooxygenase hydroxylase large subunit; Component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane. Also involved in the degradation of acetone via the O2-dependent hydroxylation of acetone. Also able to catalyze the oxidation of phenol, methylethylketone (2-butanone), 1-propanol and 2-propanol.
 
     0.781
groL-3
Chaperonin GroL; Plays an essential role in the productive folding of MimA and MimC, and thus in the formation of the active MimABCD complex. Belongs to the chaperonin (HSP60) family.
       0.746
ABK72761.1
Antibiotic biosynthesis monooxygenase; Identified by match to protein family HMM PF03992.
 
    0.721
ABK72679.1
Toluate 1,2-dioxygenase electron transfer component; Identified by match to protein family HMM PF00106; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF07729; match to protein family HMM PF08021.
 
 
 0.654
mimR
Sigma factor; Acts as a transcriptional activator of the mimABCD operon encoding the propane 2-monooxygenase complex.
 
    0.629
ABK71082.1
Putative sigma 54 type regulator; Identified by match to protein family HMM PF01590; match to protein family HMM PF02954.
 
    0.478
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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