Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK76210.1L-carnitine dehydratase/bile acid-inducible protein F; Identified by match to protein family HMM PF02515; Belongs to the CoA-transferase III family. (388 aa)    
Predicted Functional Partners:
ABK73670.1
isovaleryl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028.
  
 
 0.836
ABK74157.1
MaoC like domain protein; Identified by match to protein family HMM PF01575.
 
 
 0.816
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.782
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.771
ABK71490.1
HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.761
ABK76181.1
L-carnitine dehydratase/bile acid-inducible protein F; Identified by match to protein family HMM PF02515; Belongs to the CoA-transferase III family.
     
  0.734
ABK75664.1
Conserved hypothetical protein.
       0.563
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
     
 0.532
ABK70169.1
Conserved hypothetical protein.
       0.499
ABK73837.1
Phenoxybenzoate dioxygenase beta subunit; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.
       0.499
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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