Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK72848.1Putative HpcE protein; Identified by match to protein family HMM PF01557. (287 aa)    
Predicted Functional Partners:
ABK71883.1
2,3-dihydroxybiphenyl 1,2-dioxygenase; Identified by match to protein family HMM PF00903.
 
  
 0.842
sucA
2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]
  
 0.821
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.756
ABK72215.1
Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.719
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; Identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970.
  
 
  0.692
ABK75821.1
Succinate dehydrogenase hydrophobic membrane anchor protein SdhD.
   
 
  0.684
argH
Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.
 
  
 0.631
ABK73908.1
Regulatory protein GntR, HTH:GntR; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.
     
 0.604
ABK72495.1
Aliphatic sulfonate binding protein; Identified by match to protein family HMM TIGR01728.
  
  
 0.581
ABK72945.1
Hypothetical protein; Identified by Glimmer2; putative.
       0.572
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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