Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK73554.1Gp15 protein. (1214 aa)    
Predicted Functional Partners:
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
      
 0.822
ABK71734.1
Rmt2 protein.
  
     0.759
ABK70135.1
Transcription regulator; Identified by match to protein family HMM PF01047.
  
     0.750
ABK69846.1
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.739
ABK74285.1
Conserved domain protein.
       0.737
ABK73417.1
Conserved hypothetical protein; Identified by match to protein family HMM PF06259; Belongs to the WXG100 family.
  
     0.708
ABK74255.1
Immunogenic protein MPT63.
  
     0.693
ABK72890.1
Conserved hypothetical protein.
  
     0.683
ABK70253.1
Conserved hypothetical protein.
  
     0.679
ABK72492.1
Conserved hypothetical protein.
  
     0.651
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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