ABK71597.1 protein (Mycolicibacterium smegmatis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ABK71597.1

HNH endonuclease domain protein; Identified by match to protein family HMM PF01844. (544 aa)

Predicted Functional Partners:

ruvC

0.785

dnaG

0.777

ABK75047.1

0.764

ABK75427.1

0.761

radA

0.576

tgt

0.547

ABK71958.1

0.546

ABK70620.1

0.539

ABK75284.1

0.523

metH

0.506

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK70620.1	ABK71597.1	MSMEG_1383	MSMEG_2148	Endonuclease IV; Identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587.	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	0.539
ABK70620.1	ABK71958.1	MSMEG_1383	MSMEG_1017	Endonuclease IV; Identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587.	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	0.468
ABK70620.1	ABK75047.1	MSMEG_1383	MSMEG_2297	Endonuclease IV; Identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587.	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	0.540
ABK70620.1	ABK75427.1	MSMEG_1383	MSMEG_1947	Endonuclease IV; Identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587.	Conserved hypothetical protein; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02200.	0.537
ABK71597.1	ABK70620.1	MSMEG_2148	MSMEG_1383	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	Endonuclease IV; Identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587.	0.539
ABK71597.1	ABK71958.1	MSMEG_2148	MSMEG_1017	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	0.546
ABK71597.1	ABK75047.1	MSMEG_2148	MSMEG_2297	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	0.764
ABK71597.1	ABK75284.1	MSMEG_2148	MSMEG_2149	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	Hypothetical protein; Identified by Glimmer2; putative.	0.523
ABK71597.1	ABK75427.1	MSMEG_2148	MSMEG_1947	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	Conserved hypothetical protein; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02200.	0.761
ABK71597.1	dnaG	MSMEG_2148	MSMEG_4482	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.777
ABK71597.1	metH	MSMEG_2148	MSMEG_4185	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.506
ABK71597.1	radA	MSMEG_2148	MSMEG_6079	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function (By similarity). Also inhibits the diadenylate cyclase activity of DisA ; Belongs to the Rec [...]	0.576
ABK71597.1	ruvC	MSMEG_2148	MSMEG_2943	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.	0.785
ABK71597.1	tgt	MSMEG_2148	MSMEG_6313	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]	0.547
ABK71958.1	ABK70620.1	MSMEG_1017	MSMEG_1383	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	Endonuclease IV; Identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587.	0.468
ABK71958.1	ABK71597.1	MSMEG_1017	MSMEG_2148	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	0.546
ABK71958.1	metH	MSMEG_1017	MSMEG_4185	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.761
ABK75047.1	ABK70620.1	MSMEG_2297	MSMEG_1383	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	Endonuclease IV; Identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587.	0.540
ABK75047.1	ABK71597.1	MSMEG_2297	MSMEG_2148	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.	0.764
ABK75047.1	dnaG	MSMEG_2297	MSMEG_4482	Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.428