STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK70844.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (376 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.936
ABK76006.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
  
  0.908
ABK71939.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
  
  0.795
ABK73432.1
Phosphotransferase enzyme family protein, putative; Identified by match to protein family HMM PF01636.
 
     0.787
ABK70757.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
  
  0.783
ABK71699.1
Dihydrokaempferol 4-reductase; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993.
       0.783
ABK70546.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
     0.735
ABK73570.1
Conserved hypothetical protein.
 
     0.726
ABK71957.1
Identified by match to protein family HMM PF04909.
 
     0.715
ABK74049.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
     0.714
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.