Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hybCHydrogenase-2, large subunit; Identified by match to protein family HMM PF00374. (535 aa)    
Predicted Functional Partners:
hybA
Hydrogenase-2, small subunit; Identified by match to protein family HMM PF01058.
 
 0.999
ABK75661.1
Peptidase M52, hydrogen uptake protein; Identified by match to protein family HMM PF01750; match to protein family HMM TIGR00072.
 
 0.962
ABK73617.1
NADH ubiquinone oxidoreductase, 20 kda subunit; Identified by match to protein family HMM PF01058.
 
 0.934
ABK72715.1
Hypothetical protein; Identified by Glimmer2; putative.
   
 
 0.906
hypD-2
Hydrogenase expression/formation protein HypD; Identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075.
 
 
 0.895
hypC-2
Hydrogenase assembly chaperone HypC/HupF; Identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074.
 
 
 0.890
hypB
Hydrogenase accessory protein HypB; Identified by match to protein family HMM PF02492; match to protein family HMM TIGR00073.
 
  
 0.871
hypF
[NiFe] hydrogenase maturation protein HypF; Identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143.
 
 
 
 0.871
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.869
hypC
Hydrogenase assembly chaperone HypC/HupF; Identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074.
 
 
 0.868
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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