STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hypBHydrogenase accessory protein HypB; Identified by match to protein family HMM PF02492; match to protein family HMM TIGR00073. (259 aa)    
Predicted Functional Partners:
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.995
hypC
Hydrogenase assembly chaperone HypC/HupF; Identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074.
 
  
 0.985
hypA-2
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.983
hypF
[NiFe] hydrogenase maturation protein HypF; Identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143.
 
   
 0.974
hypD
Hydrogenase expression/formation protein HypD; Identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075.
 
  
 0.972
hypC-2
Hydrogenase assembly chaperone HypC/HupF; Identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074.
 
  
 0.972
hypE
Hydrogenase expression/formation protein HypE; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124.
 
  
 0.959
hypF-2
[NiFe] hydrogenase maturation protein HypF; Identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143.
 
   
 0.951
hypD-2
Hydrogenase expression/formation protein HypD; Identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075.
 
  
 0.947
hypC-3
Hydrogenase assembly chaperone HypC/HupF; Identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074.
 
  
 0.927
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.