Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABK70217.1Ribonucleoside-diphosphate reductase, alpha subunit; Identified by match to protein family HMM PF00317; match to protein family HMM PF02867; match to protein family HMM TIGR02506. (706 aa)    
Predicted Functional Partners:
ABK72117.1
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
 0.987
ABK71415.1
Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268.
 
 0.987
nrdB
Ribonucleoside-diphosphate reductase, beta subunit; Probable oxidase that might be involved in lipid metabolism. Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
  
 0.970
ABK71958.1
Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.
 
 0.960
ABK75047.1
Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.
 
 0.960
ABK74759.1
Conserved hypothetical protein; Identified by match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.
   
 0.911
ABK70667.1
Thymidylate kinase; Identified by match to protein family HMM PF02223.
  
 
 0.849
hutH
Histidine ammonia-lyase; Identified by similarity to EGAD:14121; match to protein family HMM PF00221; match to protein family HMM TIGR01225.
      
 0.831
pruA
1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.
  
  
 0.830
hpf
S30AE family protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
     
 0.818
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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