Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ABK70136.1D-lactate dehydrogenase; Identified by match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913. (952 aa)    
Predicted Functional Partners:
ABK72679.1
Toluate 1,2-dioxygenase electron transfer component; Identified by match to protein family HMM PF00106; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF07729; match to protein family HMM PF08021.
  
 0.978
ABK70099.1
Ferredoxin-dependent glutamate synthase 1; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
  
 
 0.970
ABK70243.1
Ferredoxin-dependent glutamate synthase 1; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
  
 
 0.970
ABK76139.1
Pyruvate synthase; Identified by match to protein family HMM PF01855.
    
 0.963
sucA
2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]
  
 
 0.952
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.914
ABK73179.1
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to protein family HMM PF01558.
    
 0.910
ABK70730.1
Transketolase, central region; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM PF02780.
   
 0.909
etfB
Electron transfer flavoprotein, beta subunit; Identified by similarity to SP:O85691; match to protein family HMM PF01012.
  
 0.905
etfA
Electron transfer flavoprotein, alpha subunit; Identified by similarity to SP:P38974; match to protein family HMM PF00766; match to protein family HMM PF01012.
  
 0.902
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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