Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABK75742.1Identified by match to protein family HMM PF07690. (463 aa)    
Predicted Functional Partners:
ABK72440.1
Amino acid transporter; Identified by match to protein family HMM PF00324.
 
   
 0.820
ABK75667.1
Identified by match to protein family HMM PF00581; match to protein family HMM PF00753.
     
 0.806
ABK69553.1
Identified by match to protein family HMM PF00753.
     
 0.805
ABK71624.1
3-oxoacyl-[acyl-carrier-protein] reductase; Identified by match to protein family HMM PF00106.
     
 0.615
lfrA
Proton antiporter efflux pump; Energy-dependent efflux pump that contributes to drug resistance. Catalyzes the efflux of norfloxacin and several related fluoroquinolones (FQ). Contributes significantly to the intrinsic MICs for ethidium bromide and acriflavine. Overexpression confers low-level resistance to hydrophilic FQ such as ciprofloxacin, ofloxacin and levofloxacin, and to ethidium bromide, acridine, acriflavine, rhodamine 123 and some quaternary ammonium compounds. May contribute to resistance to certain beta-lactams. Probably uses the proton motive force.
     
 0.514
ABK70542.1
Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.
     
 0.504
ABK73259.1
Transporter, major facilitator family protein; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
  
     0.497
ABK72073.1
4-hydroxybenzoate transporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF06779; match to protein family HMM PF07690.
 
     0.497
ABK75421.1
Transporter, major facilitator family protein; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
 
 
 0.497
ABK73236.1
Conserved hypothetical protein.
  
 
 0.494
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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