Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK72811.1Thiopurine S-methyltransferase (tpmt) superfamily protein; Identified by match to protein family HMM PF05724. (226 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
 
 0.869
ABK69940.1
Putative methyltransferase; Identified by match to protein family HMM PF05401.
     
 0.830
ABK74204.1
ATPase associated with various cellular activities, AAA-5; Identified by match to protein family HMM PF07728.
     
 0.829
ABK72024.1
Flavin-type hydroxylase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494.
      
 0.824
ABK73791.1
Oxalate decarboxylase OxdC, putative; Identified by match to protein family HMM PF00190; match to protein family HMM PF07883.
      
 0.824
ABK70454.1
Rifampin ADP-ribosyl transferase.
     
 0.769
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.732
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.732
ABK70090.1
MarR-family protein transcriptional regulator; Identified by match to protein family HMM PF01047.
 
     0.680
ABK69999.1
Hypothetical protein; Identified by Glimmer2; putative.
   
 0.669
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: medium (54%) [HD]