Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK72219.1Conserved hypothetical protein. (100 aa)    
Predicted Functional Partners:
ABK74795.1
Transcriptional regulator, MerR family protein.
  
    0.790
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), probably stimulating transcriptions from principal, but not alternative sigma factor promoters (By similarity). Partially restores transcription in the presence of rifampicin (Rif) in vitro; overexpression leads to an increase in the Rif tolerance in vivo, with smaller colonies. Seems to act by removing Rif from its binding site and preventing its further binding. No longer stimulates transcription in Rif-resistant RNA polymerase (with mutations in rpoB).
  
     0.774
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
     0.770
ABK72472.1
DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144.
  
    0.763
ABK73832.1
Conserved hypothetical protein.
 
     0.761
ABK73676.1
Conserved hypothetical protein.
  
     0.758
clgR
Transcriptional regulator, XRE family protein; Probably controls the response to vancomycin treatment; vancomycin induces expression of the clp regulon (clpP1, clpP2 and clpC1).
  
     0.755
ABK72286.1
ATPase involved in DNA repair; Identified by match to protein family HMM PF03993.
  
    0.754
ABK75909.1
Integral membrane protein.
  
     0.748
ABK72160.1
Conserved hypothetical protein.
  
     0.744
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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