Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK76195.1OB-fold nucleic acid binding domain protein; Identified by match to protein family HMM PF01336. (123 aa)    
Predicted Functional Partners:
ABK75715.1
Probable conserved integral membrane alanine and leucine rich protein.
       0.861
ABK72993.1
Amino acid permease; Identified by match to protein family HMM PF00324.
 
     0.763
ABK74825.1
TrkB protein; Identified by match to protein family HMM PF02080; match to protein family HMM PF02254.
 
    0.756
ABK70379.1
TrkA protein; Identified by match to protein family HMM PF02254.
 
    0.746
ABK73171.1
Conserved hypothetical protein; Identified by match to protein family HMM TIGR03083; match to protein family HMM TIGR03085.
 
   
 0.647
ABK70069.1
Conserved hypothetical protein.
       0.626
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
  
  
 0.615
ABK71106.1
35 kDa protein; Identified by match to protein family HMM PF04012.
  
  
 0.604
htpX
Putative protease HtpX; Identified by match to protein family HMM PF01435; Belongs to the peptidase M48B family.
   
  
 0.576
ABK76083.1
Cyclase/dehydrase; Identified by match to protein family HMM PF03364.
  
   
 0.538
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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