Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK72993.1Amino acid permease; Identified by match to protein family HMM PF00324. (664 aa)    
Predicted Functional Partners:
ABK70379.1
TrkA protein; Identified by match to protein family HMM PF02254.
 
   
 0.886
ABK74825.1
TrkB protein; Identified by match to protein family HMM PF02080; match to protein family HMM PF02254.
 
   
 0.869
ABK75612.1
Putative RNA methyltransferase; Cg2084; identified by match to protein family HMM PF01938; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
     
 0.863
ABK76195.1
OB-fold nucleic acid binding domain protein; Identified by match to protein family HMM PF01336.
 
     0.763
ABK74343.1
Alpha-amylase 3; Identified by match to protein family HMM PF00128.
  
 0.595
ABK74424.1
Identified by match to protein family HMM PF00128.
  
 0.595
glgE
Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
  
 0.595
treS
Trehalose synthase; Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation. Maltose is the preferred substrate. To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D- glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose. TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Might also functio [...]
  
 0.595
ABK72850.1
Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155.
 
 
 0.571
ABK73171.1
Conserved hypothetical protein; Identified by match to protein family HMM TIGR03083; match to protein family HMM TIGR03085.
  
   
 0.471
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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