Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK75712.1Conserved hypothetical protein. (193 aa)    
Predicted Functional Partners:
ABK70095.1
Identified by match to protein family HMM PF00570; match to protein family HMM PF01612.
 
    0.955
ABK71061.1
Conserved hypothetical protein; Identified by match to protein family HMM PF06778.
 
     0.832
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), probably stimulating transcriptions from principal, but not alternative sigma factor promoters (By similarity). Partially restores transcription in the presence of rifampicin (Rif) in vitro; overexpression leads to an increase in the Rif tolerance in vivo, with smaller colonies. Seems to act by removing Rif from its binding site and preventing its further binding. No longer stimulates transcription in Rif-resistant RNA polymerase (with mutations in rpoB).
  
     0.754
ABK72472.1
DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144.
  
    0.753
ABK73069.1
Integral membrane protein.
  
     0.747
ABK73832.1
Conserved hypothetical protein.
  
     0.718
ABK72160.1
Conserved hypothetical protein.
  
     0.713
ABK72219.1
Conserved hypothetical protein.
  
    0.712
ABK73778.1
Conserved hypothetical protein.
  
     0.704
ABK72177.1
Dolichyl-phosphate-mannose-protein mannosyltransferase; Identified by match to protein family HMM PF02366.
  
     0.700
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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