Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ABK72635.13-ketosteroid dehydrogenase; Identified by match to protein family HMM PF00890. (522 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  
 0.869
ABK72215.1
Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.841
ABK74479.1
Identified by match to protein family HMM PF03061.
 
   
 0.810
ABK76139.1
Pyruvate synthase; Identified by match to protein family HMM PF01855.
    
 0.781
ABK73179.1
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to protein family HMM PF01558.
    
 0.768
sucA
2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]
    
 0.765
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family.
  
  
 0.756
ABK71075.1
Biphenyl-2,3-diol 1,2-dioxygenase 1; Identified by match to protein family HMM PF00903.
  
     0.740
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Identified by match to protein family HMM PF01039.
    
  0.724
ABK69944.1
Acetyl-coenzyme a carboxylase carboxyl transferase; Identified by match to protein family HMM PF01039.
    
  0.724
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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