Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK70902.13-ketosteroid-delta-1-dehydrogenase; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266. (558 aa)    
Predicted Functional Partners:
ABK70591.1
Oxygenase KshA; Identified by match to protein family HMM PF00355.
 
 
 0.993
kshA
Rieske [2Fe-2S] domain protein; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A.
 
  
 0.977
ABK72155.1
Oxidoreductase, NAD/FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.
 
 
 0.974
kshB
Oxidoreductase, electron transfer component; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A.
 
 
 0.974
ABK74714.1
Lipid-transfer protein.
 
 0.971
ABK75049.1
Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355.
 
 
 0.954
ABK73724.1
Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355.
 
  
 0.953
ABK71225.1
Nuclear transport factor 2 (NTF2) domain superfamily protein; Identified by match to protein family HMM PF02136.
 
  
  0.952
ABK74307.1
Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.
  
 
 0.943
ABK71760.1
3-ketosteroid-delta4; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266.
 
 
 
0.943
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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