STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK71760.13-ketosteroid-delta4; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266. (529 aa)    
Predicted Functional Partners:
ABK74714.1
Lipid-transfer protein.
  
  
  0.971
ksdD
3-ketosteroid dehydrogenase; Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids. Is also involved in the formation of 1,4-androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to.
 
  
 
0.956
ABK71225.1
Nuclear transport factor 2 (NTF2) domain superfamily protein; Identified by match to protein family HMM PF02136.
  
 
 0.952
ABK70902.1
3-ketosteroid-delta-1-dehydrogenase; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266.
 
 
 
0.943
ABK70591.1
Oxygenase KshA; Identified by match to protein family HMM PF00355.
 
 
 0.935
ABK70837.1
3-ketosteroid dehydrogenase; Identified by match to protein family HMM PF00890.
 
  
 
0.903
ABK73927.1
FAD binding domain, putative; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266.
 
  
 
0.806
ABK71566.1
3-beta hydroxysteroid dehydrogenase/isomerase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993.
     
 0.803
ABK74064.1
Conserved hypothetical protein.
 
     0.791
kshA
Rieske [2Fe-2S] domain protein; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A.
  
  
 0.774
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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