| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK69697.1 | ABK69759.1 | MSMEG_1925 | MSMEG_0029 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.952 |
| ABK69697.1 | ABK74300.1 | MSMEG_1925 | MSMEG_2111 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity. | 0.968 |
| ABK69697.1 | ABK75414.1 | MSMEG_1925 | MSMEG_4524 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate synthase component I; Identified by match to protein family HMM PF00425. | 0.959 |
| ABK69697.1 | aroA | MSMEG_1925 | MSMEG_1890 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.530 |
| ABK69697.1 | aroB | MSMEG_1925 | MSMEG_3033 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.504 |
| ABK69697.1 | aroC | MSMEG_1925 | MSMEG_3030 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.977 |
| ABK69697.1 | aroE | MSMEG_1925 | MSMEG_3028 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Shikimate-5-dehydrogenase; Identified by match to protein family HMM PF01488; match to protein family HMM TIGR01809; Belongs to the shikimate dehydrogenase family. | 0.630 |
| ABK69697.1 | aroK-2 | MSMEG_1925 | MSMEG_3031 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.421 |
| ABK69697.1 | pabB | MSMEG_1925 | MSMEG_5446 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Para-aminobenzoate synthase, component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 0.513 |
| ABK69697.1 | trpE | MSMEG_1925 | MSMEG_3217 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.957 |
| ABK69759.1 | ABK69697.1 | MSMEG_0029 | MSMEG_1925 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | 0.952 |
| ABK69759.1 | ABK74300.1 | MSMEG_0029 | MSMEG_2111 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity. | 0.959 |
| ABK69759.1 | ABK75414.1 | MSMEG_0029 | MSMEG_4524 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Anthranilate synthase component I; Identified by match to protein family HMM PF00425. | 0.997 |
| ABK69759.1 | aroA | MSMEG_0029 | MSMEG_1890 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.524 |
| ABK69759.1 | aroB | MSMEG_0029 | MSMEG_3033 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.752 |
| ABK69759.1 | aroC | MSMEG_0029 | MSMEG_3030 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.978 |
| ABK69759.1 | aroE | MSMEG_0029 | MSMEG_3028 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Shikimate-5-dehydrogenase; Identified by match to protein family HMM PF01488; match to protein family HMM TIGR01809; Belongs to the shikimate dehydrogenase family. | 0.775 |
| ABK69759.1 | aroK-2 | MSMEG_0029 | MSMEG_3031 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.619 |
| ABK69759.1 | pabB | MSMEG_0029 | MSMEG_5446 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Para-aminobenzoate synthase, component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 0.999 |
| ABK69759.1 | trpE | MSMEG_0029 | MSMEG_3217 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
