Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK73249.1Beta-lactamase; Identified by match to protein family HMM PF00144. (400 aa)    
Predicted Functional Partners:
ABK74610.1
Thiopurine S-methyltransferase (tpmt) superfamily protein; Identified by match to protein family HMM PF03848; match to protein family HMM PF05724.
 
     0.698
ABK73340.1
Monooxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494.
       0.600
ABK70350.1
Steroid monooxygenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF07992.
 
  
  0.564
ABK70888.1
Steroid monooxygenase; Identified by match to protein family HMM PF01266.
 
  
  0.564
ABK71230.1
Steroid monooxygenase; Identified by match to protein family HMM PF01266.
 
  
  0.563
dacB
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Carboxypeptidase that cleaves terminal D-alanine from peptidoglycan in the mycobacterial cell wall. May cleave L-Lys-D-Ala and/or D-Ala-D-Ala peptide bonds. Exerts important effects on mycobacterial cell morphology and cell division. Belongs to the peptidase S13 family.
    
 0.552
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
    0.517
pyrR
PyrR bifunctional protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
       0.485
pyrB
Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
       0.485
ABK73071.1
Integral membrane protein.
       0.484
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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