STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
moxRIdentified by match to protein family HMM PF07726; match to protein family HMM PF07728. (348 aa)    
Predicted Functional Partners:
ABK72529.1
Conserved hypothetical protein.
  
 0.979
ABK70345.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00092.
 
 
 0.964
ABK74689.1
Protein of unknown function DUF58, putative.
 
  
 0.822
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.667
ABK72979.1
Identified by match to protein family HMM PF01022.
   
  
 0.555
ABK72305.1
Beta-lactamase; Identified by match to protein family HMM PF00144.
      
 0.530
ABK70868.1
Lipoprotein; Identified by match to protein family HMM PF01882.
 
  
 0.506
ABK72276.1
Chelatase; Identified by match to protein family HMM PF00092; match to protein family HMM PF01078; match to protein family HMM PF07728.
  
 
 0.470
inhA
[NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...]
  
    0.468
fabG-3
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.461
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.