Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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fabG-33-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)    
Predicted Functional Partners:
ABK74048.1
3-oxoacyl-[acyl-carrier-protein] synthase 2; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.997
ABK73355.1
3-oxoacyl-[acyl-carrier-protein] synthase 1; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.997
ABK69838.1
3-oxoacyl-[acyl-carrier-protein] synthase 2; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.997
inhA
[NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...]
 
 
 0.989
ABK74163.1
Identified by match to protein family HMM PF01575.
 
 0.978
ABK71596.1
Conserved hypothetical protein.
 
 
 0.977
ABK76059.1
Conserved hypothetical protein; Belongs to the UPF0336 family.
 
 0.967
ABK73491.1
Conserved hypothetical protein; Belongs to the UPF0336 family.
 
 0.964
ABK74527.1
Conserved hypothetical protein; Belongs to the UPF0336 family.
 
 0.961
ABK73909.1
MaoC like domain protein; Identified by match to protein family HMM PF01575.
 
 0.957
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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