| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK71806.1 | ABK72982.1 | MSMEG_1488 | MSMEG_3285 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | 0.975 |
| ABK71806.1 | ABK74373.1 | MSMEG_1488 | MSMEG_4460 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | Acetolactate synthase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.940 |
| ABK71806.1 | ilvA | MSMEG_1488 | MSMEG_3183 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.985 |
| ABK71806.1 | ilvB | MSMEG_1488 | MSMEG_2372 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.977 |
| ABK71806.1 | ilvE | MSMEG_1488 | MSMEG_4276 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | Branched-chain amino acid aminotransferase; Catalyzes the reversible transfers of an amino group from glutamate to the alpha-ketoacid of the respective amino acid in the final step in the biosynthesis of branchedchain amino acids. The amino acids can be ranked in the following order with respect to their efficiency as amino donor: Leu > Ile > Val. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.503 |
| ABK71806.1 | ilvN | MSMEG_1488 | MSMEG_2373 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | Acetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119; Belongs to the acetolactate synthase small subunit family. | 0.993 |
| ABK71806.1 | leuB | MSMEG_1488 | MSMEG_2379 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.974 |
| ABK71806.1 | thrC | MSMEG_1488 | MSMEG_4956 | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.458 |
| ABK72982.1 | ABK71806.1 | MSMEG_3285 | MSMEG_1488 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | 0.975 |
| ABK72982.1 | ABK74373.1 | MSMEG_3285 | MSMEG_4460 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | Acetolactate synthase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.926 |
| ABK72982.1 | ilvA | MSMEG_3285 | MSMEG_3183 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.971 |
| ABK72982.1 | ilvB | MSMEG_3285 | MSMEG_2372 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.978 |
| ABK72982.1 | ilvE | MSMEG_3285 | MSMEG_4276 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | Branched-chain amino acid aminotransferase; Catalyzes the reversible transfers of an amino group from glutamate to the alpha-ketoacid of the respective amino acid in the final step in the biosynthesis of branchedchain amino acids. The amino acids can be ranked in the following order with respect to their efficiency as amino donor: Leu > Ile > Val. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.601 |
| ABK72982.1 | ilvN | MSMEG_3285 | MSMEG_2373 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | Acetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119; Belongs to the acetolactate synthase small subunit family. | 0.988 |
| ABK72982.1 | leuB | MSMEG_3285 | MSMEG_2379 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.905 |
| ABK72982.1 | thrC | MSMEG_3285 | MSMEG_4956 | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.573 |
| ABK74373.1 | ABK71806.1 | MSMEG_4460 | MSMEG_1488 | Acetolactate synthase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776. | 0.940 |
| ABK74373.1 | ABK72982.1 | MSMEG_4460 | MSMEG_3285 | Acetolactate synthase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Identified by match to protein family HMM PF00180. | 0.926 |
| ABK74373.1 | ilvA | MSMEG_4460 | MSMEG_3183 | Acetolactate synthase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.984 |
| ABK74373.1 | ilvB | MSMEG_4460 | MSMEG_2372 | Acetolactate synthase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.976 |
