STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
glgXGlycogen debranching enzyme GlgX; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; Belongs to the glycosyl hydrolase 13 family. (718 aa)    
Predicted Functional Partners:
malQ
4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217.
 
 0.998
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
 
 
 0.998
ABK72491.1
Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.
 
 
 0.994
treS
Trehalose synthase; Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation. Maltose is the preferred substrate. To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D- glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose. TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Might also functio [...]
 
 
 0.992
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
 
  
 0.987
glgE
Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
 
  
 0.969
ABK74343.1
Alpha-amylase 3; Identified by match to protein family HMM PF00128.
 
 
 0.965
treZ
Malto-oligosyltrehalose trehalohydrolase; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.
  
0.928
ABK71455.1
Glycosyl hydrolase, family protein 57; Identified by match to protein family HMM PF03065; Belongs to the glycosyl hydrolase 57 family.
  
 
 0.916
mak
Trehalose synthase-fused probable maltokinase; Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate (Probable). Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB.
 
  
 0.912
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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