Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK72924.1Identified by match to protein family HMM PF01408. (361 aa)    
Predicted Functional Partners:
ABK72514.1
Short-chain dehydrogenase/reductase SDR; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    0.830
ABK74828.1
Identified by match to protein family HMM PF01261.
 
 
 0.825
ABK72228.1
IolE protein; Identified by match to protein family HMM PF01261.
 
 
 0.815
ABK69613.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
    0.780
ABK74864.1
Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.
  
  
  0.709
impA
Inositol monophosphate phosphatase; Catalyzes the dephosphorylation of inositol 1-phosphate (I-1- P) to yield free myo-inositol, a key metabolite in mycobacteria.
  
 
 0.628
ABK72681.1
Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459.
  
 
 0.627
ABK69903.1
Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily.
  
 
 0.627
ABK72163.1
Nucleotide-sugar dehydrogenase; Identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 
 0.602
ABK72686.1
IolD protein; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
 
  
 0.590
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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