Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ABK71887.1Carboxylic ester hydrolase; Identified by match to protein family HMM PF03403. (482 aa)    
Predicted Functional Partners:
ABK72514.1
Short-chain dehydrogenase/reductase SDR; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    0.613
nnrD
Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]
     
 0.568
ABK76129.1
Succinate semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171.
       0.563
ABK72924.1
Identified by match to protein family HMM PF01408.
  
    0.560
ABK69613.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
  
 0.558
ABK70479.1
Integral membrane protein DUF6; Identified by match to protein family HMM PF00892.
       0.469
ABK71727.1
Patatin; Identified by match to protein family HMM PF01734.
 
 
 0.435
ABK75365.1
Oxidoreductase; Identified by match to protein family HMM PF01494.
  
     0.427
ABK70529.1
Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.
 
   
 0.425
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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