Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABK75617.1Conserved hypothetical protein; Identified by match to protein family HMM PF06738. (507 aa)    
Predicted Functional Partners:
ABK69833.1
Conserved hypothetical protein.
  
     0.674
ABK76080.1
Probable conserved transmembrane protein; Identified by match to protein family HMM PF04600; match to protein family HMM TIGR02958.
  
     0.672
eccE1
Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in at least a donor strain.
  
     0.669
ABK69818.1
Conserved hypothetical protein.
  
  
 0.660
ABK72616.1
Probable conserved integral membrane protein; Identified by match to protein family HMM PF02517.
 
     0.596
eccB1
Conserved hypothetical protein; An ATPase (shown for residues 72-479). Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains ; Belongs to the EccB family.
 
     0.581
ABK74495.1
Identified by match to protein family HMM PF01580.
  
   
 0.571
pknB
Serine-threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins (By similarity). Probably phosphorylates RseA.
       0.550
sun
Ribosomal RNA small subunit methyltransferase B; Identified by match to protein family HMM PF01029; match to protein family HMM PF01189; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
       0.550
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
       0.550
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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