Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ABK71848.1N5,N10-methylene- tetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296. (339 aa)    
Predicted Functional Partners:
hydA
Dihydropyrimidinase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02033.
 
     0.913
ABK75274.1
Hydrolase; Identified by match to protein family HMM PF00795.
 
     0.906
hydA-2
Dihydropyrimidinase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02033.
 
     0.770
hydA-3
Dihydropyrimidinase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02033.
 
     0.769
ABK74201.1
Integral membrane transporter; Identified by match to protein family HMM PF02133.
 
     0.728
ABK72942.1
Monooxygenase; Identified by match to protein family HMM PF00296.
  
  
  0.668
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.656
ABK73368.1
Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026.
  
   
 0.617
ABK75334.1
Conserved hypothetical protein TIGR00026; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026.
 
   
 0.613
ABK76236.1
MmcI protein.
  
     0.578
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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