| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK70103.1 | ABK74866.1 | MSMEG_4757 | MSMEG_2657 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | 0.609 |
| ABK70103.1 | dnaK | MSMEG_4757 | MSMEG_0709 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.520 |
| ABK70103.1 | groL | MSMEG_4757 | MSMEG_0880 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.678 |
| ABK70103.1 | groL-2 | MSMEG_4757 | MSMEG_1583 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.678 |
| ABK70103.1 | groL-3 | MSMEG_4757 | MSMEG_1978 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | Chaperonin GroL; Plays an essential role in the productive folding of MimA and MimC, and thus in the formation of the active MimABCD complex. Belongs to the chaperonin (HSP60) family. | 0.678 |
| ABK70103.1 | ileS | MSMEG_4757 | MSMEG_3169 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.692 |
| ABK70103.1 | lon | MSMEG_4757 | MSMEG_3582 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.821 |
| ABK70103.1 | rpsB | MSMEG_4757 | MSMEG_2519 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | Ribosomal protein S2; Identified by match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family. | 0.817 |
| ABK70103.1 | sucA | MSMEG_4757 | MSMEG_5049 | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | 2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...] | 0.980 |
| ABK74866.1 | ABK70103.1 | MSMEG_2657 | MSMEG_4757 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | 0.609 |
| ABK74866.1 | dnaK | MSMEG_2657 | MSMEG_0709 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.548 |
| ABK74866.1 | groL | MSMEG_2657 | MSMEG_0880 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.771 |
| ABK74866.1 | groL-2 | MSMEG_2657 | MSMEG_1583 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.740 |
| ABK74866.1 | groL-3 | MSMEG_2657 | MSMEG_1978 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | Chaperonin GroL; Plays an essential role in the productive folding of MimA and MimC, and thus in the formation of the active MimABCD complex. Belongs to the chaperonin (HSP60) family. | 0.740 |
| ABK74866.1 | grpE | MSMEG_2657 | MSMEG_0710 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.478 |
| ABK74866.1 | ileS | MSMEG_2657 | MSMEG_3169 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.602 |
| ABK74866.1 | lon | MSMEG_2657 | MSMEG_3582 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.801 |
| ABK74866.1 | rpsB | MSMEG_2657 | MSMEG_2519 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | Ribosomal protein S2; Identified by match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family. | 0.676 |
| ABK74866.1 | sucA | MSMEG_2657 | MSMEG_5049 | Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family. | 2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...] | 0.916 |
| dnaK | ABK70103.1 | MSMEG_0709 | MSMEG_4757 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801. | 0.520 |
