Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK71543.1Oxidoreductase, zinc-binding dehydrogenase family protein; Identified by match to protein family HMM PF00107. (348 aa)    
Predicted Functional Partners:
ABK74742.1
Sorbitol utilization protein SOU2; Identified by match to protein family HMM PF00106.
  
 
 0.820
ABK70442.1
PTS system, Fru family protein, IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
  
 
 0.815
ABK72360.1
Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; Identified by match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.802
ABK75370.1
Ribose transport ATP-binding protein RbsA; Identified by match to protein family HMM PF00005.
  
  
 0.799
ABK70755.1
Sorbitol dehydrogenase; Identified by match to protein family HMM PF00107.
 
    
0.748
thpA
Sugar-binding transcriptional regulator, LacI family protein; Part of an ABC transporter complex involved in D-threitol import. Binds D-threitol. Functions in the transport for the degradation pathway of D-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source; Belongs to the bacterial solute-binding protein 2 family.
  
    0.674
xypA
Periplasmic sugar-binding proteins; Part of an ABC transporter complex likely involved in xylitol import. Binds xylitol.
  
    0.596
ABK74292.1
Oxidoreductase, zinc-binding dehydrogenase family protein; Identified by match to protein family HMM PF00107.
  
     0.572
dthD
Short chain dehydrogenase; Catalyzes the NAD-dependent reversible oxidation of D- threitol. Involved in the degradation pathway of D-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source. Does not catalyze the oxidation of xylitol, L-sorbitol, and L-sorbose. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.564
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
 
 0.554
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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