Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ureG-2Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (228 aa)    
Predicted Functional Partners:
ureB
Urease, beta subunit; Identified by match to protein family HMM PF00699; match to protein family HMM TIGR00192; Belongs to the urease beta subunit family.
 
  
 0.985
ureC-2
Urease, alpha subunit; Identified by match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM TIGR01792; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.952
ureA
Urease, gamma subunit; Identified by match to protein family HMM PF00547; match to protein family HMM TIGR00193; Belongs to the urease gamma subunit family.
 
  
 0.941
ABK71702.1
Conserved hypothetical protein.
 
 
 0.934
ABK72481.1
Urease accessory protein uref.
 
 
 0.927
ABK73901.1
Urease gamma/beta subunit; Identified by match to protein family HMM PF00547; match to protein family HMM PF00699; match to protein family HMM TIGR00192; match to protein family HMM TIGR00193.
 
  
 0.863
ureC
Urease, alpha subunit; Identified by match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01792.
 
  
 0.850
ABK72983.1
Urease accessory protein UreF; Identified by match to protein family HMM PF01730.
 
 
 0.842
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.822
hypA-2
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.818
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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