Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
ABK72667.1Major facilitator superfamily protein MFS_1; Probably plays a role in bacterial growth and resistance to antibiotics. (429 aa)    
Predicted Functional Partners:
galK
Galactokinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR00131; Belongs to the GHMP kinase family. GalK subfamily.
  
   
 0.829
ABK74529.1
ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
      
 0.814
lfrA
Proton antiporter efflux pump; Energy-dependent efflux pump that contributes to drug resistance. Catalyzes the efflux of norfloxacin and several related fluoroquinolones (FQ). Contributes significantly to the intrinsic MICs for ethidium bromide and acriflavine. Overexpression confers low-level resistance to hydrophilic FQ such as ciprofloxacin, ofloxacin and levofloxacin, and to ethidium bromide, acridine, acriflavine, rhodamine 123 and some quaternary ammonium compounds. May contribute to resistance to certain beta-lactams. Probably uses the proton motive force.
      
 0.769
ABK72520.1
Major facilitator superfamily protein; Identified by match to protein family HMM PF07690.
 
 
 0.717
ABK70670.1
3-alpha-hydroxysteroid dehydrogenase; Identified by match to protein family HMM PF01370.
       0.714
ABK72240.1
D-galactonate transporter; Identified by match to protein family HMM PF07690.
 
 
 0.689
ABK73259.1
Transporter, major facilitator family protein; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
 
 
 0.570
ABK71841.1
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
      
 0.558
ABK75869.1
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
      
 0.549
ABK71448.1
ABC transporter ATP-binding protein; Identified by match to protein family HMM PF00005.
      
 0.544
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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