eda-2 protein (Mycolicibacterium smegmatis) - STRING interaction network

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eda-2

2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182. (209 aa)

Predicted Functional Partners:

ABK76135.1

0.982

edd

0.920

ABK74739.1

0.905

sucA

0.865

ABK73220.1

0.859

ABK75134.1

0.857

ABK74357.1

0.857

aceA

0.849

aceA-2

0.849

glcB

0.848

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK73220.1	ABK76135.1	MSMEG_3786	MSMEG_3785	D-amino acid deaminase.	PfkB-family protein carbohydrate kinase; Identified by match to protein family HMM PF00294.	0.683
ABK73220.1	eda-2	MSMEG_3786	MSMEG_3788	D-amino acid deaminase.	2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.	0.859
ABK74357.1	ABK75134.1	MSMEG_5037	MSMEG_0301	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	0.935
ABK74357.1	aceA	MSMEG_5037	MSMEG_0911	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.	0.938
ABK74357.1	aceA-2	MSMEG_5037	MSMEG_3706	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.	0.938
ABK74357.1	eda-2	MSMEG_5037	MSMEG_3788	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.	0.857
ABK74357.1	glcB	MSMEG_5037	MSMEG_3640	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.	0.946
ABK74357.1	sucA	MSMEG_5037	MSMEG_5049	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]	0.952
ABK74739.1	ABK76135.1	MSMEG_2908	MSMEG_3785	2-Keto-3-deoxy-gluconate kinase; Identified by match to protein family HMM PF00294.	PfkB-family protein carbohydrate kinase; Identified by match to protein family HMM PF00294.	0.757
ABK74739.1	eda-2	MSMEG_2908	MSMEG_3788	2-Keto-3-deoxy-gluconate kinase; Identified by match to protein family HMM PF00294.	2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.	0.905
ABK74739.1	edd	MSMEG_2908	MSMEG_0313	2-Keto-3-deoxy-gluconate kinase; Identified by match to protein family HMM PF00294.	Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.	0.736
ABK75134.1	ABK74357.1	MSMEG_0301	MSMEG_5037	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	0.935
ABK75134.1	aceA	MSMEG_0301	MSMEG_0911	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.	0.938
ABK75134.1	aceA-2	MSMEG_0301	MSMEG_3706	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.	0.938
ABK75134.1	eda-2	MSMEG_0301	MSMEG_3788	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.	0.857
ABK75134.1	glcB	MSMEG_0301	MSMEG_3640	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.	0.946
ABK75134.1	sucA	MSMEG_0301	MSMEG_5049	Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.	2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]	0.952
ABK76135.1	ABK73220.1	MSMEG_3785	MSMEG_3786	PfkB-family protein carbohydrate kinase; Identified by match to protein family HMM PF00294.	D-amino acid deaminase.	0.683
ABK76135.1	ABK74739.1	MSMEG_3785	MSMEG_2908	PfkB-family protein carbohydrate kinase; Identified by match to protein family HMM PF00294.	2-Keto-3-deoxy-gluconate kinase; Identified by match to protein family HMM PF00294.	0.757
ABK76135.1	eda-2	MSMEG_3785	MSMEG_3788	PfkB-family protein carbohydrate kinase; Identified by match to protein family HMM PF00294.	2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.	0.982

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