STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK72328.1Identified by match to protein family HMM PF00756. (454 aa)    
Predicted Functional Partners:
ABK71774.1
Polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801.
 
 
 0.790
lysX
lysyl-tRNA synthetase; Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine res [...]
 
   
 0.719
pks
Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801.
  
 0.699
pks5
Mycocerosic acid synthase; Polyketide synthase involved in the biosynthesis of 2,4- dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis.
  
 
 0.663
ABK73953.1
LppW protein.
  
   
 0.629
ABK70013.1
Oxidoreductase, zinc-binding dehydrogenase family protein; Identified by match to protein family HMM PF00107.
  
 0.614
ABK69584.1
Alcohol dehydrogenase B; Identified by match to protein family HMM PF00107.
  
 0.614
ABK75278.1
Alcohol dehydrogenase 1; Identified by match to protein family HMM PF00107.
  
 0.614
ABK72362.1
Aryl-alcohol dehydrogenase; Identified by match to protein family HMM PF00107.
  
 0.614
ABK75122.1
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107.
  
 0.614
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (32%) [HD]