Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK75086.1Universal stress protein family protein, putative; Identified by match to protein family HMM PF00582. (147 aa)    
Predicted Functional Partners:
ABK72172.1
Identified by match to protein family HMM PF00582.
      
 0.810
ABK70370.1
Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes.
  
  
 0.799
ABK71187.1
PAP2 superfamily protein; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Could be involved in the dephosphorylation of decaprenylphosphoryl-5-phosphoribose (DPPR) to decaprenyl-phospho- ribose (DPR); Belongs to the PA-phosphatase related phosphoesterase family.
 
   
 0.530
ABK72533.1
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
   
 0.525
crgA
Putative membrane protein; Involved in cell division; Belongs to the CrgA family.
  
   
 0.523
ABK76136.1
Adenylate cyclase, family protein 3; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672.
  
   
 0.520
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.513
ABK73781.1
Amino acid-binding ACT; Identified by match to protein family HMM PF01842.
 
  
 0.494
ABK72645.1
Adenylate cyclase, family protein 3; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672.
  
   
 0.475
ABK75395.1
Conserved hypothetical protein.
  
  
 0.466
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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