Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK72793.1Conserved hypothetical protein. (152 aa)    
Predicted Functional Partners:
ABK71695.1
Putative TetR-family protein transcriptional regulator; Identified by match to protein family HMM PF00440.
 
     0.831
ABK71752.1
YesF protein.
  
    0.789
ABK73536.1
Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561.
  
     0.545
ABK70884.1
Beta-lactamase; Identified by match to protein family HMM PF00753.
 
    0.521
ABK73527.1
Integral membrane protein.
       0.521
rpsA
30S ribosomal protein S1; Binds mRNA, facilitating recognition of most mRNAs by the 30S ribosomal subunit during translation initiation (By similarity). Plays a role in trans-translation; binds tmRNA (the product of the ssrA gene). Binds very poorly to pyrazinoic acid (POA), the active form of the prodrug pyrazinamide (PZA); POA does not disrupt trans-translation in this organism. M.smegmatis is resistant to the antibiotic PZA. In trans-translation Ala-aminoacylated transfer-messenger RNA (tmRNA, product of the ssrA gene; the 2 termini fold to resemble tRNA(Ala) while it encodes a shor [...]
       0.442
ABK71375.1
TetR-family protein transcriptional regulator; Identified by match to protein family HMM PF00440.
 
     0.418
ABK73077.1
TetR-family protein transcriptional regulator; Identified by match to protein family HMM PF00440.
 
     0.418
ABK72161.1
Conserved domain protein.
  
     0.411
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.