Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cobNCobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. (1211 aa)    
Predicted Functional Partners:
cobO
cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF02572; match to protein family HMM TIGR00708.
 
 
 0.997
cobB
Cobyrinic Acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.996
cobL
precorrin-6Y C5,15-methyltransferase (decarboxylating); Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469.
 
  
 0.994
ABK72276.1
Chelatase; Identified by match to protein family HMM PF00092; match to protein family HMM PF01078; match to protein family HMM PF07728.
 
 0.987
cobK
Precorrin-6x reductase; Identified by match to protein family HMM PF02571; match to protein family HMM TIGR00715.
 
   
 0.964
ABK69847.1
ATP:cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.963
cobM
Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; Belongs to the precorrin methyltransferase family.
 
  
 0.954
cobU
Cobinamide kinase / cobinamide phosphate guanyltransferase; Identified by match to protein family HMM PF02283.
 
 
 0.937
ABK72513.1
Cobalamin biosynthesis protein cobIJ; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family.
 
  
 0.932
ABK70641.1
precorrin-8X methylmutase; Identified by match to protein family HMM PF02570.
 
  
 0.880
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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