Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobMPrecorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; Belongs to the precorrin methyltransferase family. (251 aa)    
Predicted Functional Partners:
ABK72513.1
Cobalamin biosynthesis protein cobIJ; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family.
 
 0.999
cobK
Precorrin-6x reductase; Identified by match to protein family HMM PF02571; match to protein family HMM TIGR00715.
 
 
 0.999
cobL
precorrin-6Y C5,15-methyltransferase (decarboxylating); Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469.
 
 0.999
cobF
precorrin-6A synthase (deacetylating); Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02434.
 
 
 0.998
cobU
Cobinamide kinase / cobinamide phosphate guanyltransferase; Identified by match to protein family HMM PF02283.
 
 
 0.990
cobO
cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF02572; match to protein family HMM TIGR00708.
  
 0.985
ABK70641.1
precorrin-8X methylmutase; Identified by match to protein family HMM PF02570.
 
 
 0.980
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.961
cobN
Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257.
 
  
 0.954
cobA
uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470.
 
 
0.936
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.