| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK72048.1 | ABK74084.1 | MSMEG_1359 | MSMEG_4259 | DeoR-family protein transcriptional regulator; Identified by match to protein family HMM PF02082; match to protein family HMM PF08220. | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | 0.691 |
| ABK72048.1 | ABK74509.1 | MSMEG_1359 | MSMEG_3888 | DeoR-family protein transcriptional regulator; Identified by match to protein family HMM PF02082; match to protein family HMM PF08220. | Conserved hypothetical protein. | 0.884 |
| ABK72048.1 | rpoA | MSMEG_1359 | MSMEG_1524 | DeoR-family protein transcriptional regulator; Identified by match to protein family HMM PF02082; match to protein family HMM PF08220. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.552 |
| ABK72048.1 | rpoB | MSMEG_1359 | MSMEG_1367 | DeoR-family protein transcriptional regulator; Identified by match to protein family HMM PF02082; match to protein family HMM PF08220. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.576 |
| ABK72048.1 | rpoC | MSMEG_1359 | MSMEG_1368 | DeoR-family protein transcriptional regulator; Identified by match to protein family HMM PF02082; match to protein family HMM PF08220. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.574 |
| ABK74084.1 | ABK72048.1 | MSMEG_4259 | MSMEG_1359 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | DeoR-family protein transcriptional regulator; Identified by match to protein family HMM PF02082; match to protein family HMM PF08220. | 0.691 |
| ABK74084.1 | ABK74509.1 | MSMEG_4259 | MSMEG_3888 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | Conserved hypothetical protein. | 0.738 |
| ABK74084.1 | rpoA | MSMEG_4259 | MSMEG_1524 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.400 |
| ABK74084.1 | rpoB | MSMEG_4259 | MSMEG_1367 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.529 |
| ABK74084.1 | sigA | MSMEG_4259 | MSMEG_2758 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | Sigma factor MysA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.778 |
| ABK74509.1 | ABK72048.1 | MSMEG_3888 | MSMEG_1359 | Conserved hypothetical protein. | DeoR-family protein transcriptional regulator; Identified by match to protein family HMM PF02082; match to protein family HMM PF08220. | 0.884 |
| ABK74509.1 | ABK74084.1 | MSMEG_3888 | MSMEG_4259 | Conserved hypothetical protein. | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | 0.738 |
| ABK74509.1 | pafA | MSMEG_3888 | MSMEG_3890 | Conserved hypothetical protein. | Proteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction likely involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine. Belongs to the Pup ligase/Pup deamidase family. Pup- conjugating enzyme subfamily. | 0.826 |
| ABK74509.1 | rbpA | MSMEG_3888 | MSMEG_3858 | Conserved hypothetical protein. | Conserved hypothetical protein; Binds to RNA polymerase (RNAP), probably stimulating transcriptions from principal, but not alternative sigma factor promoters (By similarity). Partially restores transcription in the presence of rifampicin (Rif) in vitro; overexpression leads to an increase in the Rif tolerance in vivo, with smaller colonies. Seems to act by removing Rif from its binding site and preventing its further binding. No longer stimulates transcription in Rif-resistant RNA polymerase (with mutations in rpoB). | 0.855 |
| ABK74509.1 | rpoA | MSMEG_3888 | MSMEG_1524 | Conserved hypothetical protein. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.906 |
| ABK74509.1 | rpoB | MSMEG_3888 | MSMEG_1367 | Conserved hypothetical protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.960 |
| ABK74509.1 | rpoC | MSMEG_3888 | MSMEG_1368 | Conserved hypothetical protein. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.914 |
| ABK74509.1 | rpoZ | MSMEG_3888 | MSMEG_3053 | Conserved hypothetical protein. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.885 |
| ABK74509.1 | sigA | MSMEG_3888 | MSMEG_2758 | Conserved hypothetical protein. | Sigma factor MysA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.934 |
| ABK74509.1 | tatA | MSMEG_3888 | MSMEG_3887 | Conserved hypothetical protein. | Twin arginine-targeting protein translocase, TatA/E family protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.764 |
