Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABK69884.1Identified by match to protein family HMM PF00582. (273 aa)    
Predicted Functional Partners:
ABK72172.1
Identified by match to protein family HMM PF00582.
      
 0.806
ABK70370.1
Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes.
  
  
 0.802
ABK75611.1
Probable conserved transmembrane protein.
  
  
 0.645
ABK74210.1
Acyltransferase, ws/dgat/mgat subfamily protein; Identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; Belongs to the long-chain O-acyltransferase family.
  
 
 0.571
ABK75395.1
Conserved hypothetical protein.
 
  
 0.562
ABK70463.1
Conserved hypothetical protein.
 
  
 0.538
ABK72096.1
Identified by match to protein family HMM PF00582.
 
   
0.506
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.464
ABK74930.1
14 kDa antigen; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.457
ABK74454.1
methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.449
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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